Pathogens… Just the word causes worry amongst
any one who knows what they are. And in brief, they’re one thing we all want to
keep away from. We lately got the possibility to speak with Milan Patel, Co-founder and CEO
of PathogenDx, a Scottsdale, AZ primarily based firm which has created a disruptive
technologies: DNA-primarily based testing for cannabis as properly as other industries.
Verify out the interview beneath to study much more
about this technologies and what it implies for cannabis growers and customers.
CM: What is
PathogenDx – in one particular sentence, and then in depth? What is the technologies in
play right here?
Patel: In one particular sentence, PathogenDx is an Arizona biotechnology
firm that has created a disruptive DNA-primarily based technologies to test for
several pathogens (bacterial and fungal organisms that result in contamination) in
a fraction of the time, price and labor to make certain cannabis, hemp, meals, ag, and
water is protected for consumption.
The globe is filled with
damaging pathogens that increasingly threaten the security of our cannabis, hemp,
meals and water provide. And however, testing labs nonetheless rely on the Petri dishes scientists
invented more than a century ago. At PathogenDx, microbial testing has now been
brought into the contemporary age. The company’s patent-winning scientists have
invented a game-altering DNA-primarily based microarray technologies (see image beneath) that
accelerates the testing identification and quantification of microbes (from
E-coli to powdery mildew)—delivering precise final results in just six hours without having
the will need for enrichment or DNA purification. The firm entered the Cannabis
industry to demonstrate the energy of the Ultra-speedy DNA microarray to prove the
capability of delivering the quickest microbial test in the cannabis sector
when meeting the security testing regulations.
CM: The important
tool in testing has normally been the Petri dish – why alter that now? How does DNA
come into play?
Patel: The Petri dish has been about for 140 years. Nonetheless, testing final results
take really extended due to the fact with a Petri dish, you have to take a sample, enrich
any bacterial or fungal organisms in that sample, streak it on an agar culture
and wait for the cells of the bacterial or fungal pathogens to develop just before you
get a outcome. This can take anyplace from three days up to 7 days. When you have a
lot of samples coming into a lab, it can be quite unwieldy.
Why alter now? – The provide chain of
cannabis, hemp, meals, agriculture and water is much more effective now, and with the
item moving by means of the provide chain substantially quicker to the finish consumer, the
threat is greater due to the fact a prospective contaminated meals is most likely to get consumed
just before final results are obtained from petri dish testing. This is evident by the
continued increases in meals borne outbreaks in the final two-three decades, and current
examples are the meals borne outbreaks at Chipotle and the Romaine lettuce
incident. Fundamentally a 19th century resolution can not meet the wants
and demands of these markets, and a 21st century resolution is required
whereby final results are delivered quicker just before contaminated finish item gets
How does DNA come into play? – DNA comes
into play due to the fact the methodology by which the course of action functions is diverse in
that it is a targeted method: you do not have to wait for the actual pathogen
cells to develop, you are capable to recognize that the item is contaminated at the
molecular level, and you can get a outcome in hours.
Patel: The greatest threats facing farmers and their cannabis/hemp crops is
continual contamination inside grows with a higher level of presence of each
bacterial and fungal microbes in the finish sample. In addition, we are beginning
to see enhanced presence of viruses – specially for hemp farmers – which is
wreaking havoc as petri dish testing can not test for viruses. This final results in
catastrophic losses each from an financial standpoint, as properly as yield
CM: Even although
PathogenDx was created for hemp and cannabis, you say it can be applied to
test other agricultural crops, water, even meat and dairy places. Will the very same
test and process be applied for diverse issues what else does PathogenDx will need
to do to enter the Meals and Dairy sphere?
Patel: We have created the technologies universally applicable to several markets
as properly as ubiquitous, in that at the base level, it is one particular course of action. Whether or not
you are testing cannabis, romaine, milk, water or something else, the course of action is
properly the very same. The content material of the kits are mainly the very same, but
occasionally enhanced with diverse bacterial or fungal organisms that are
distinct to that market.
at present submitting the use of the technologies as a certified technique to the
AOAC for meals and environmental testing at the federal level. We count on to have
certification by mid-2020, and when that occurs, PathogenDx will have access
to a $30B industry. In addition, we are establishing a test that can test up to 20
pathogens that are at present causing excellent concerns in the milk and dairy
market. We strategy to introduce a item in 2020 for this industry.
CM: What’s subsequent
for PathogenDx in 2020? Exactly where else do you see application of this technologies?
Patel: We are expanding the applications of the technologies into the Meals,
Environmental, Dairy markets, as properly as introducing a plant pathogen kit that
will broaden the testing capability in cannabis, hemp and Agriculture. The technologies has prospective into the substantially bigger clinical
diagnostics with a multitude of clinical applications. At the present time, the
firm is operating with many collaborators to evaluate essential industry